Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CTSE | P14091 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19613593 | 0.85 | SCN8A (0.42) | STSP2RX3SCN1ASCN8AMEN1 | |
| SCHEMBL19627593 | 0.81 | SCN8A (0.42) | STSSCN1ASCN8AMEN1KMT2A | |
| SCHEMBL19634012 | 0.80 | PDE4B (0.41) | STSP2RX3SCN1ASCN8AMEN1 | |
| SCHEMBL19634031 | 0.78 | STS (0.36) | STSP2RX3SCN1ASCN8AMEN1 | |
| SCHEMBL19634256 | 0.77 | P2RX3 (0.37) | STSP2RX3SCN1ASCN8AMEN1 | |
| SCHEMBL19634114 | 0.75 | SCN1A (0.37) | P2RX3SCN1ASCN8AMEN1KMT2A | |
| SCHEMBL28528260 | 0.74 | STS (0.39) | STSP2RX3SCN1ASCN8AMEN1 | |
| SCHEMBL19634176 | 0.72 | P2RX3 (0.36) | STSP2RX3MEN1KMT2AMAPT | |
| SCHEMBL19617773 | 0.72 | SCN1A (0.37) | SCN1ASCN8AMEN1KMT2AMAPT | |
| SCHEMBL19634129 | 0.71 | SCN8A (0.47) | SCN1ASCN8AMEN1KMT2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |