Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20843379 | 1.00 | RIPK1 (0.39) | RIPK1KCNH2SCN3AIDH1GPR119 | |
| SCHEMBL19803547 | 1.00 | RIPK1 (0.39) | RIPK1KCNH2SCN3AIDH1GPR119 | |
| SCHEMBL20835922 | 0.85 | KCNH2 (0.38) | RIPK1KCNH2SCN3AALDH1A1LIPE | |
| SCHEMBL20835798 | 0.85 | KCNH2 (0.38) | RIPK1KCNH2SCN3AOPRM1OPRL1 | |
| SCHEMBL20835919 | 0.85 | KCNH2 (0.38) | RIPK1KCNH2SCN3AALDH1A1LIPE | |
| SCHEMBL20843433 | 0.85 | KCNH2 (0.38) | RIPK1KCNH2SCN3AALDH1A1LIPE | |
| SCHEMBL20835800 | 0.85 | KCNH2 (0.38) | RIPK1KCNH2SCN3AOPRM1OPRL1 | |
| SCHEMBL19803653 | 0.85 | KCNH2 (0.38) | RIPK1KCNH2SCN3AALDH1A1LIPE | |
| SCHEMBL22451589 | 0.74 | GRIA4 (0.39) | RIPK1KCNH2SCN3APKMHTR2A | |
| SCHEMBL20843431 | 0.74 | GRIA4 (0.39) | RIPK1KCNH2SCN3APKMHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |