Hydrazine

Hydrazine

SCHEMBL28528440

NN.Nc1ccc(C2=CCC(N)(C(=O)O)C=C2)cc1

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP7 P09237 1/20 0.32
MMP9 P14780 1/20 0.32
MMP13 P45452 1/20 0.32
CYP3A4 P08684 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
TAAR1 Q96RJ0 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2121108 0.85 SRR (0.32) TDP1TP53
SCHEMBL4352973 0.77 GRIA2 (0.36) CYP3A4
SCHEMBL2403790 0.76 CYP3A4 (0.40) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
SCHEMBL30010410 0.75 CYP3A4 (0.36) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
SCHEMBL4394628 0.74 GRM4 (0.33)
SCHEMBL28359754 0.72 CYP19A1 (0.33) HSD17B10ALDH1A1
SCHEMBL2543904 0.71 CYP3A4 (0.36) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL29144452 0.70 CYP3A4 (0.34) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
SCHEMBL714828 0.70 CYP3A4 (0.39) CYP3A4TDP1TAAR1HSD17B10ALDH1A1
Sulfuric Acid SCHEMBL8640324 0.70 TDP1 (0.33) CYP3A4TDP1TAAR1HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112390959-B Metal organic framework material containing Schiff base ligand, catalyst, preparation and application 中国科学院大连化学物理研究所 2021-07-13 CN disclosed
CN-112390959-A Metal organic framework material containing Schiff base ligand, catalyst, preparation and application 中国科学院大连化学物理研究所 2021-02-23 CN disclosed