⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335461 | 0.70 | — | — | |
| SCHEMBL66883 | 0.67 | — | — | |
| SCHEMBL18788393 | 0.67 | — | — | |
| SCHEMBL8227653 | 0.64 | — | — | |
| SCHEMBL15047 | 0.64 | — | — | |
| Isopropyl Alcohol SCHEMBL10579294 | 0.64 | — | — | |
| Isopropyl Alcohol SCHEMBL7807855 | 0.64 | — | — | |
| Isopropyl Alcohol SCHEMBL20338127 | 0.64 | ALDH1A1 (0.75) | — | |
| SCHEMBL13208844 | 0.64 | — | — | |
| Isopropyl Alcohol SCHEMBL2590415 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240737-A1 | ENZYME-PRODRUG THERAPY FOR PROSTHETIC JOINT REPAIR | ACADEMISCH ZIEKENHUIS LEIDEN (NL) | 2010-09-23 | — | — | US | disclosed |
| US-7674454-B2 | Enzyme-prodrug therapy for prosthetic joint repair | INNOVATA LIMITED (GB) | 2010-03-09 | — | — | US | disclosed |
| EP-1725267-B1 | ENZYME-PRODRUG THERAPY FOR PROSTHETIC JOINT REPAIR | INNOVATA LTD (GB) | 2010-02-24 | — | — | EP | disclosed |
| EP-1406910-B1 | PREPARATION METHODS OF DERIVATIVES OF BISPHOSPHONATES | UNIV PARIS 13 (FR) | 2010-01-13 | — | — | EP | disclosed |
| EP-1725267-A2 | ENZYME-PRODRUG THERAPY FOR PROSTHETIC JOINT REPAIR | Innovata PLC (GB) | 2006-11-29 | — | — | EP | disclosed |
| US-7005533-B2 | Bisphosphonate derivatives, their preparations and uses | UNIVERSITE PARIS 13 (FR) | 2006-02-28 | — | — | US | disclosed |
| US-20050260160-A1 | Enzyme-prodrug therapy for prosthetic joint repair | ACADEMISCH ZIEKENHUIS LEIDEN (NL) | 2005-11-24 | — | — | US | disclosed |
| WO-2005084713-A2 | ENZYME-PRODRUG THERAPY FOR PROSTHETIC JOINT REPAIR | INNOVATA PLC (GB) | 2005-09-15 | — | — | WO | disclosed |
| US-20040266735-A1 | Bisphosphonate derivatives, their preparations and uses | UNIVERSITE PARIS 13 | 2004-12-30 | — | — | US | disclosed |
| EP-1406910-A1 | NOVEL BISPHOSPHONATE DERIVATIVES, THEIR PREPARATION METHODS AND USES | Universite Paris 13 (FR) | 2004-04-14 | — | — | EP | disclosed |
| US-20030036537-A1 | Bisphosphonate derivatives, their preparations and uses | UNIVERSITE PARIS, 13 (FR) | 2003-02-20 | — | — | US | disclosed |
| WO-2003008425-A1 | NOVEL BISPHOSPHONATE DERIVATIVES, THEIR PREPARATION METHODS AND USES | UNIVERSITE PARIS 13 (FR) | 2003-01-30 | — | — | WO | disclosed |