Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 4/20 | 0.56 |
| ▸ | IKBKB | O14920 | 4/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.51 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.51 |
| ▸ | CDC7 | O00311 | 5/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 2/20 | 0.49 |
| ▸ | CCNC | P24863 | 4/20 | 0.49 |
| ▸ | CDK8 | P49336 | 4/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448102 | 0.87 | BCAT2 (0.67) | CHUKIKBKBBCAT2CASP1IKBKE | |
| SCHEMBL25306948 | 0.86 | SIRT3 (0.61) | CHUKIKBKBBCAT2CASP1IKBKE | |
| SCHEMBL164881 | 0.86 | BCAT2 (0.71) | CHUKIKBKBBCAT2CASP1IKBKE | |
| Hydrochloric Acid SCHEMBL4597839 | 0.85 | BCAT2 (0.69) | CHUKIKBKBBCAT2CASP1IKBKE | |
| Hydrochloric Acid SCHEMBL29710331 | 0.85 | BCAT2 (0.69) | CHUKIKBKBBCAT2CASP1IKBKE | |
| Hydrochloric Acid SCHEMBL9027847 | 0.85 | BCAT2 (0.69) | CHUKIKBKBBCAT2CASP1IKBKE | |
| SCHEMBL28829405 | 0.82 | CHEK2 (0.52) | CHUKIKBKBCASP1IKBKEPKMYT1 | |
| SCHEMBL27193217 | 0.80 | CHUK (0.61) | CHUKIKBKBCASP1IKBKEPKMYT1 | |
| SCHEMBL27193240 | 0.79 | CHUK (0.55) | CHUKIKBKBCASP1IKBKEPKMYT1 | |
| SCHEMBL27996934 | 0.78 | CCNC (0.55) | CHUKIKBKBCASP1IKBKEPKMYT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729916-A | Benzodioxane modulators of leukotriene A4 hydrolase (LTA 4H) for the prevention and treatment of aging-related diseases | 万能溶剂有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-112469439-A | With leukotriene A4Hydrolase modulators for the treatment of aging-related diseases | 万能溶剂有限公司 | 2021-03-09 | — | — | CN | disclosed |