Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761089 | 0.85 | MAPK1 (0.54) | MAPK1L3MBTL1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL14662373 | 0.83 | PPIA (0.66) | MAPK1ALDH1A1HPGDSMN1; SMN2TSHR | |
| Nitric Acid SCHEMBL27571319 | 0.81 | MAPK1 (0.50) | MAPK1L3MBTL1ALOX15HSD17B10ALDH1A1 | |
| Nitric Acid SCHEMBL6162457 | 0.81 | MAPK1 (0.50) | MAPK1L3MBTL1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL4353650 | 0.80 | MAPT (0.63) | MAPK1HSD17B10ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16471129 | 0.80 | MEN1 (0.46) | MAPK1ALOX15ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6975312 | 0.80 | MAPT (0.54) | MAPK1L3MBTL1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL6975308 | 0.80 | MAPT (0.54) | MAPK1L3MBTL1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL28717653 | 0.79 | PPIA (0.55) | MAPK1ALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL29654264 | 0.79 | PPIA (0.55) | MAPK1ALDH1A1HPGDSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107674040-B | Method for converting febuxostat impurities into febuxostat | 天津力生制药股份有限公司 | 2021-02-19 | — | — | CN | disclosed |