Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | P4HB | P07237 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877355 | 0.91 | ALDH1A1 (0.76) | ALDH1A1KMT2ATSHRHTTMAPT | |
| SCHEMBL9585968 | 0.88 | KMT2A (0.70) | ALDH1A1KMT2ATSHRHTTMAPT | |
| SCHEMBL6521808 | 0.88 | KMT2A (0.53) | ALDH1A1KMT2ATSHRHTTMAPT | |
| SCHEMBL25947449 | 0.86 | ALDH1A1 (0.69) | ALDH1A1KMT2ATSHRHTTMAPT | |
| SCHEMBL25946421 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2ATSHRHTTMAPT | |
| SCHEMBL25947070 | 0.84 | TSHR (0.58) | ALDH1A1KMT2ATSHRHTTMAPT | |
| SCHEMBL25946349 | 0.82 | ALDH1A1 (0.74) | ALDH1A1KMT2ATSHRHTTMAPT | |
| SCHEMBL25947796 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KMT2ATSHRHTTMAPT | |
| SCHEMBL15497247 | 0.80 | KMT2A (0.71) | ALDH1A1KMT2ATSHRHTTMAPT | |
| SCHEMBL25941803 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KMT2ATSHRHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213660-B1 | 5-SUBSTITUTED INDOL-3-CARBOXYLIC ACID DERIVATIVES EXHIBITING ANTIVIRAL ACTIVITY A METHOD FOR THE PRODUCTION AND USE THEREOF | RES AND DEV COMPANY MEDBIOPHARM LTD (RU) | 2012-12-12 | — | — | EP | disclosed |
| EP-2213660-A1 | 5-SUBSTITUTED INDOL-3-CARBOXYLIC ACID DERIVATIVES EXHIBITING ANTIVIRAL ACTIVITY A METHOD FOR THE PRODUCTION AND USE THEREOF | Obschestvo S Ogranichennoy Otvetstvennostju "Binatekh" (RU) | 2010-08-04 | — | — | EP | disclosed |