Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.67 |
| ▸ | INSR | P06213 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28542463 | 0.93 | EGFR (0.68) | EGFRINSRIGF1RALK | |
| SCHEMBL28533887 | 0.92 | EGFR (0.70) | EGFR | |
| SCHEMBL28530455 | 0.91 | EGFR (0.79) | EGFRINSRIGF1RALK | |
| SCHEMBL28531481 | 0.90 | EGFR (0.61) | EGFR | |
| SCHEMBL22821976 | 0.89 | EGFR (0.84) | EGFRINSRIGF1RALK | |
| SCHEMBL22821819 | 0.89 | EGFR (0.84) | EGFRINSRIGF1RALK | |
| SCHEMBL22026205 | 0.86 | EGFR (0.69) | EGFRINSRIGF1RALK | |
| SCHEMBL28610266 | 0.86 | EGFR (0.58) | EGFRINSRIGF1RALK | |
| SCHEMBL28529250 | 0.85 | EGFR (0.63) | EGFRINSRIGF1RALK | |
| SCHEMBL28536021 | 0.85 | EGFR (0.70) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513029-A | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-03-16 | — | — | CN | disclosed |