Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.69 |
| ▸ | INSR | P06213 | 2/20 | 0.56 |
| ▸ | IGF1R | P08069 | 2/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22025925 | 0.94 | EGFR (0.79) | EGFR | |
| SCHEMBL28525327 | 0.91 | EGFR (0.64) | EGFRINSRIGF1RALK | |
| SCHEMBL22026202 | 0.88 | EGFR (0.88) | EGFR | |
| SCHEMBL26387622 | 0.87 | EGFR (0.68) | EGFRINSRIGF1RALK | |
| SCHEMBL28529635 | 0.87 | EGFR (0.58) | EGFRINSRIGF1RALK | |
| SCHEMBL24954085 | 0.87 | EGFR (0.69) | EGFR | |
| SCHEMBL28529314 | 0.86 | EGFR (0.67) | EGFRINSRIGF1RALK | |
| SCHEMBL28533887 | 0.86 | EGFR (0.70) | EGFR | |
| SCHEMBL28541898 | 0.86 | EGFR (0.68) | EGFR | |
| SCHEMBL28529250 | 0.86 | EGFR (0.63) | EGFRINSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656769-B1 | ARYL-PHOSPHORUS-OXYGEN COMPOUND AS EGFR KINASE INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2023-01-25 | — | — | EP | disclosed |
| EP-3656769-A1 | ARYL-PHOSPHORUS-OXYGEN COMPOUND AS EGFR KINASE INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-05-27 | — | — | EP | disclosed |