Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546538 | 0.81 | ADH1B (0.50) | TAAR1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL2469837 | 0.78 | TAAR1 (0.58) | TAAR1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL97848 | 0.77 | TAAR1 (0.52) | TAAR1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL10133721 | 0.77 | RECQL (0.59) | KMT2AALDH1A1SMN1; SMN2HTTNPSR1 | |
| SCHEMBL10518854 | 0.77 | TAAR1 (0.43) | TAAR1MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9320773 | 0.76 | CA12 (0.37) | KDM4EADH1BADH1CADH1AADH7 | |
| SCHEMBL5925042 | 0.76 | MEN1 (0.38) | TAAR1MEN1KMT2AALDH1A1TDP1 | |
| Formic Acid SCHEMBL5071551 | 0.74 | TAAR1 (0.53) | TAAR1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9818247 | 0.73 | TAAR1 (0.48) | TAAR1MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2473716 | 0.73 | TAAR1 (0.62) | TAAR1HDAC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |