SCHEMBL28529489

SCHEMBL28529489

CC(=O)C(F)Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.53
PKM P14618 1/20 0.53
PTGS1 P23219 1/20 0.53
XIAP P98170 1/20 0.53
SLC7A5 Q01650 1/20 0.53
CYP1A2 P05177 1/20 0.52
CTRB1 P17538 4/20 0.50
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
ALPL P05186 1/20 0.47
POLB P06746 1/20 0.47
ALPG P10696 1/20 0.47
MDM2 Q00987 1/20 0.47
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
LMNA P02545 1/20 0.46
SLC15A1 P46059 1/20 0.46
CPA1 P15085 2/20 0.46
CPA3 P15088 2/20 0.46
FOLH1 Q04609 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246475 0.83 CYP1A2 (0.61) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL28090728 0.83 CYP1A2 (0.56) ALPIPKMPTGS1XIAPSLC7A5
Ammonia Solution, Strong SCHEMBL38660546 0.81 CYP1A2 (0.59) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL6964952 0.81 CYP1A2 (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7279699 0.80 ATM (0.54) CYP1A2CTRB1NPC1RAB9APOLB
SCHEMBL12271851 0.79 CYP1A2 (0.57) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL29020043 0.79 EPHX1 (0.58) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7810193 0.79 CYP1A2 (0.52) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL11097150 0.79 NPC1 (0.49) CYP1A2CTRB1NPC1RAB9A
SCHEMBL497369 0.78 CYP1A2 (0.68) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321398-B Method for synthesizing alpha-fluorinated ketone by hydrazonating aliphatic chain monoketone 中山大学 2021-11-23 CN disclosed
CN-112321398-A Method for synthesizing alpha-fluorinated ketone by hydrazonating aliphatic chain monoketone 中山大学 2021-02-05 CN disclosed