Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.49 |
| ▸ | EGFR | P00533 | 6/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28522018 | 0.83 | EGFR (0.56) | PTGER4PTGER2EGFR | |
| SCHEMBL28521215 | 0.77 | EGFR (0.54) | PTGER4PTGER2EGFRPTGER3 | |
| SCHEMBL17821579 | 0.75 | PTGER4 (0.64) | PTGER4PTGER2PTGER3PTGER1HDAC8 | |
| SCHEMBL17821580 | 0.75 | PTGER4 (0.64) | PTGER4PTGER2PTGER3PTGER1HDAC8 | |
| SCHEMBL17821791 | 0.74 | PTGER4 (0.62) | PTGER4PTGER2PTGER3PTGER1HDAC8 | |
| SCHEMBL17821551 | 0.74 | PTGER4 (0.62) | PTGER4PTGER2PTGER3PTGER1HDAC8 | |
| SCHEMBL22555973 | 0.74 | PTGER4 (0.62) | PTGER4PTGER2PTGER3PTGER1HDAC8 | |
| SCHEMBL17821793 | 0.74 | PTGER4 (0.62) | PTGER4PTGER2PTGER3PTGER1HDAC8 | |
| SCHEMBL28522610 | 0.74 | PTGER4 (0.62) | PTGER4PTGER2PTGER3PTGER1HDAC8 | |
| SCHEMBL28908592 | 0.74 | PTGER4 (0.62) | PTGER4PTGER2PTGER3PTGER1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808031-B | Ferulic acid derivative and preparation method and application thereof | 湖南中医药大学 | 2022-01-14 | — | — | CN | disclosed |
| CN-111808031-A | Ferulic acid derivative and preparation method and application thereof | 湖南中医药大学 | 2020-10-23 | — | — | CN | disclosed |