Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.56 |
| ▸ | RET | P07949 | 9/20 | 0.52 |
| ▸ | KIF5B | P33176 | 6/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 6/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28522615 | 0.90 | EGFR (0.57) | EGFRRETKIF5BERBB2ERBB4 | |
| SCHEMBL28530529 | 0.87 | EGFR (0.54) | EGFRRETKIF5BKDR | |
| SCHEMBL28518401 | 0.86 | EGFR (0.53) | EGFRERBB2KDR | |
| SCHEMBL28529605 | 0.86 | EGFR (0.53) | EGFRERBB2ERBB4KDR | |
| SCHEMBL28521215 | 0.85 | EGFR (0.54) | EGFRRETKIF5BERBB2ERBB4 | |
| SCHEMBL28908571 | 0.85 | EGFR (0.53) | EGFRRETKIF5BERBB2ERBB4 | |
| SCHEMBL28518408 | 0.84 | EGFR (0.51) | EGFRERBB2ERBB4KDR | |
| SCHEMBL28521195 | 0.84 | KDR (0.65) | EGFRRETKIF5BKDRAURKB | |
| SCHEMBL28527871 | 0.84 | EGFR (0.51) | EGFRERBB2ERBB4KDR | |
| SCHEMBL28529600 | 0.83 | PTGER4 (0.49) | EGFRPTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808031-B | Ferulic acid derivative and preparation method and application thereof | 湖南中医药大学 | 2022-01-14 | — | — | CN | disclosed |
| CN-111808031-A | Ferulic acid derivative and preparation method and application thereof | 湖南中医药大学 | 2020-10-23 | — | — | CN | disclosed |