SCHEMBL28529627

SCHEMBL28529627

O=C(c1ccccc1)c1ccc(CN2CCOCC2)cc1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.68
EPAS1 Q99814 1/20 0.68
ALDH1A1 P00352 2/20 0.67
HPGD P15428 2/20 0.61
GAA P10253 1/20 0.60
RAB9A P51151 7/20 0.59
NPC1 O15118 5/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
HTT P42858 2/20 0.59
HRH3 Q9Y5N1 2/20 0.58
CA2 P00918 1/20 0.57
KMT2A Q03164 1/20 0.56
LMNA P02545 1/20 0.56
MAPK1 P28482 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MAPT P10636 1/20 0.56
KDM4E B2RXH2 1/20 0.56
ABCB1 P08183 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8027548 0.94 HPGD (0.68) HIF1AEPAS1ALDH1A1HPGDRAB9A
Hydrochloric Acid SCHEMBL27789112 0.92 HPGD (0.66) HIF1AEPAS1ALDH1A1HPGDRAB9A
SCHEMBL13266931 0.91 HPGD (0.61) HIF1AEPAS1ALDH1A1HPGDRAB9A
Succinic Acid SCHEMBL27767598 0.89 HPGD (0.59) HIF1AEPAS1ALDH1A1HPGDRAB9A
SCHEMBL2929466 0.88 NPC1 (0.71) HIF1AEPAS1ALDH1A1HPGDRAB9A
SCHEMBL20224022 0.87 HIF1A (0.63) HIF1AEPAS1ALDH1A1HPGDGAA
SCHEMBL20227103 0.87 HIF1A (0.63) HIF1AEPAS1ALDH1A1HPGDGAA
SCHEMBL11192966 0.87 CA2 (0.64) HIF1AEPAS1ALDH1A1HPGDRAB9A
SCHEMBL2928330 0.86 SMN1; SMN2 (0.64) HIF1AEPAS1ALDH1A1HPGDRAB9A
Hydrochloric Acid SCHEMBL11194321 0.85 CA2 (0.65) HIF1AEPAS1ALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110198756-B Lubricious insertion tool for medical devices and methods of using same 舒尔默迪克斯公司 2022-07-12 CN disclosed
CN-110167626-B Low friction seal 苏尔莫迪克斯公司 2021-12-21 CN disclosed
CN-108348728-B Hemodialysis catheter sleeve 苏尔莫迪克斯公司 2021-07-09 CN disclosed
CN-107666872-B Insertable medical device system with plaque treatment portion and method of use thereof 舒尔默迪克斯公司 2021-05-18 CN disclosed
CN-106794283-B Article coating comprising oligomeric polyphenol layer and methods of biological use thereof 舒尔默迪克斯公司 2021-03-02 CN disclosed
CN-108697825-B Lubricious coatings having surface salt groups 苏尔莫迪克斯公司 2021-02-12 CN disclosed