Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21746057 | 0.93 | APLNR (0.44) | APLNRHDAC6METAP2HRH1KCNH2 | |
| SCHEMBL29435725 | 0.93 | APLNR (0.44) | APLNRHDAC6METAP2HRH1KCNH2 | |
| SCHEMBL179299 | 0.73 | APLNR (0.51) | APLNRHDAC6HRH1KCNH2JAK2 | |
| SCHEMBL9839014 | 0.73 | — | — | |
| SCHEMBL30318775 | 0.72 | APLNR (0.56) | APLNRHDAC6HRH1KCNH2JAK2 | |
| SCHEMBL13063990 | 0.72 | APLNR (0.44) | APLNRHDAC6HRH1KCNH2JAK2 | |
| SCHEMBL1857413 | 0.71 | APLNR (0.50) | APLNRHDAC6HRH1KCNH2JAK2 | |
| SCHEMBL17765315 | 0.71 | APLNR (0.46) | APLNRHDAC6 | |
| SCHEMBL25203689 | 0.70 | APLNR (0.57) | APLNRHDAC6HRH1KCNH2JAK2 | |
| SCHEMBL20743678 | 0.70 | APLNR (0.49) | APLNRHDAC6HRH1KCNH2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109526219-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2021-03-12 | — | — | CN | disclosed |