Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.84 |
| ▸ | HRH1 | P35367 | 12/20 | 0.84 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.84 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.84 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.66 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852985 | 1.00 | HRH3 (0.84) | HRH3HRH1ADRA1BADRA1AKCNH2 | |
| Formic Acid SCHEMBL4144418 | 0.98 | HRH3 (0.81) | HRH3HRH1ADRA1BADRA1AKCNH2 | |
| SCHEMBL2850271 | 0.91 | HRH3 (1.00) | HRH3HRH1ADRA1BADRA1AKCNH2 | |
| SCHEMBL2850269 | 0.91 | HRH3 (1.00) | HRH3HRH1ADRA1BADRA1AKCNH2 | |
| SCHEMBL4144415 | 0.86 | HRH3 (0.74) | HRH3HRH1ADRA1BADRA1AKCNH2 | |
| SCHEMBL2846839 | 0.83 | HRH3 (0.83) | HRH3HRH1ADRA1BADRA1AKCNH2 | |
| SCHEMBL2851067 | 0.80 | HRH3 (1.00) | HRH3HRH1ADRA1BADRA1AKCNH2 | |
| SCHEMBL13438225 | 0.79 | HRH3 (1.00) | HRH3HRH1ADRA1BADRA1AKCNH2 | |
| SCHEMBL13438221 | 0.79 | HRH3 (1.00) | HRH3HRH1ADRA1BADRA1AKCNH2 | |
| SCHEMBL2854990 | 0.78 | HRH3 (0.81) | HRH3HRH1ADRA1BADRA1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027108-B1 | HISTAMINE RECEPTOR ANTAGONISTS COMPRISING AN AZEPIN CORE | GLAXO GROUP LTD (GB) | 2010-01-13 | — | — | EP | disclosed |