Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20345730 | 1.00 | ATF4 (0.47) | ATF4PRMT5WDR77CTSLKDM4E | |
| SCHEMBL21617359 | 0.89 | PRMT5 (0.39) | ATF4PRMT5WDR77KDM4EALDH1A1 | |
| SCHEMBL1809033 | 0.78 | ATF4 (0.42) | ATF4PRMT5WDR77CTSLPDE4D | |
| SCHEMBL1809034 | 0.78 | ATF4 (0.42) | ATF4PRMT5WDR77CTSLPDE4D | |
| SCHEMBL601403 | 0.76 | ATF4 (0.41) | ATF4PRMT5WDR77KDM4EALDH1A1 | |
| SCHEMBL21378728 | 0.76 | ATF4 (0.41) | ATF4PRMT5WDR77KDM4EALDH1A1 | |
| SCHEMBL31567590 | 0.73 | EPHX1 (0.36) | ATF4CTSLLMNAPDE4DMAPK8 | |
| SCHEMBL24158831 | 0.71 | KAT2B (0.42) | ATF4PRMT5WDR77ALDH1A1PDE4D | |
| SCHEMBL1813151 | 0.71 | KMT2A (0.39) | ATF4PRMT5WDR77ALDH1A1LMNA | |
| SCHEMBL1813150 | 0.71 | KMT2A (0.39) | ATF4PRMT5WDR77ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149961-B | Azabicyclo-substituted triazole derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-113149961-A | Azabicyclo-substituted triazole derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-109071492-B | Azabicyclo-substituted triazole derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-02-26 | — | — | CN | disclosed |