Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 5/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28907087 | 0.90 | CALCRL (0.48) | RIPK1NTRK1JAK2PDE5ACALCRL | |
| SCHEMBL28521349 | 0.88 | RIPK1 (0.50) | RIPK1NTRK1JAK2PDE5ACALCRL | |
| SCHEMBL20835904 | 0.88 | RIPK1 (0.50) | RIPK1NTRK1JAK2PDE5ACALCRL | |
| SCHEMBL20835879 | 0.86 | RIPK1 (0.48) | RIPK1NTRK1JAK2PDE5ACALCRL | |
| SCHEMBL20835797 | 0.86 | RIPK1 (0.48) | RIPK1NTRK1JAK2PDE5ACALCRL | |
| SCHEMBL28907112 | 0.86 | RIPK1 (0.48) | RIPK1NTRK1JAK2PDE5ACALCRL | |
| SCHEMBL28521345 | 0.85 | RIPK1 (0.47) | RIPK1NTRK1JAK2PDE5ACALCRL | |
| SCHEMBL28518941 | 0.85 | RIPK1 (0.47) | RIPK1NTRK1JAK2PDE5ACALCRL | |
| SCHEMBL28908006 | 0.84 | RIPK1 (0.49) | RIPK1NTRK1JAK2PDE5AGPR119 | |
| SCHEMBL21093659 | 0.84 | RIPK1 (0.35) | RIPK1NTRK1JAK2PDE5ACALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |