Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CETP | P11597 | 3/20 | 0.54 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135437 | 1.00 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR | |
| Benzyl Tetradecanoate SCHEMBL351857 | 0.98 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR | |
| SCHEMBL872955 | 0.98 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR | |
| Hexadecanoic Acid Benzyl Ester SCHEMBL1356933 | 0.98 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR | |
| SCHEMBL9802928 | 0.98 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR | |
| SCHEMBL3836540 | 0.98 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR | |
| SCHEMBL7564307 | 0.98 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR | |
| SCHEMBL6832768 | 0.98 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR | |
| SCHEMBL296362 | 0.98 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR | |
| SCHEMBL1322235 | 0.98 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPK1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112494656-B | Insulin receptor partial agonists | 默沙东有限责任公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-113453724-A | Sulfonylmaleimide-based linkers and corresponding conjugates | 皮埃尔法布雷医药公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-108064173-B | Partial insulin receptor agonists | 默沙东公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112494656-A | Partial insulin receptor agonists | 默沙东公司 | 2021-03-16 | — | — | CN | disclosed |