Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936187 | 1.00 | TSHR (0.62) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL8564404 | 0.97 | — | — | |
| SCHEMBL22445024 | 0.85 | TSHR (0.38) | TSHRFAAHTRPV1ALDH1A1TDP1 | |
| SCHEMBL11203071 | 0.82 | TSHR (0.33) | TSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL350393 | 0.81 | TSHR (0.84) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL7180877 | 0.81 | TSHR (0.75) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL10448536 | 0.81 | TSHR (0.84) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL1684008 | 0.81 | TSHR (0.84) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL7189299 | 0.81 | TSHR (0.84) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL27740716 | 0.81 | TSHR (0.84) | TSHRFAAHTRPV1HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469439-A | With leukotriene A4Hydrolase modulators for the treatment of aging-related diseases | 万能溶剂有限公司 | 2021-03-09 | — | — | CN | disclosed |