Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.61 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.55 |
| ▸ | ITK | Q08881 | 1/20 | 0.55 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944339 | 1.00 | DYRK1A (0.61) | DYRK1ARIPK1ITKRIPK3HDAC3 | |
| SCHEMBL28530314 | 0.89 | DYRK1A (0.69) | DYRK1ARIPK1RIPK3HDAC3HDAC4 | |
| SCHEMBL30944386 | 0.89 | DYRK1A (0.69) | DYRK1ARIPK1RIPK3HDAC3HDAC4 | |
| SCHEMBL28525158 | 0.88 | DYRK1A (0.68) | DYRK1ARIPK1ITKRIPK3HDAC3 | |
| SCHEMBL30944330 | 0.88 | DYRK1A (0.68) | DYRK1ARIPK1ITKRIPK3HDAC3 | |
| SCHEMBL30944348 | 0.88 | DYRK1A (0.68) | DYRK1ARIPK1ITKRIPK3HDAC3 | |
| SCHEMBL28908448 | 0.88 | DYRK1A (0.68) | DYRK1ARIPK1ITKRIPK3HDAC3 | |
| Hydrochloric Acid SCHEMBL18154343 | 0.87 | DYRK1A (0.67) | DYRK1ARIPK1ITKRIPK3HDAC3 | |
| SCHEMBL30944377 | 0.86 | DYRK1A (0.66) | DYRK1ARIPK1ITKRIPK3HDAC3 | |
| SCHEMBL28516330 | 0.86 | DYRK1A (0.66) | DYRK1ARIPK1ITKRIPK3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112423746-A | Novel anti-mycobacterial heterocyclic amides | 克莱斯通公司 | 2021-02-26 | — | — | CN | claimed |
| CN-112423746-A | Novel anti-mycobacterial heterocyclic amides | 克莱斯通公司 | 2021-02-26 | — | — | CN | disclosed |