Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CLK1 | P49759 | 1/20 | 0.60 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.59 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525158 | 1.00 | DYRK1A (0.68) | DYRK1ANPC1RAB9AALDH1A1MAOA | |
| SCHEMBL28908448 | 1.00 | DYRK1A (0.68) | DYRK1ANPC1RAB9AALDH1A1MAOA | |
| SCHEMBL30944330 | 1.00 | DYRK1A (0.68) | DYRK1ANPC1RAB9AALDH1A1MAOA | |
| Hydrochloric Acid SCHEMBL18154343 | 0.99 | DYRK1A (0.67) | DYRK1ANPC1RAB9AALDH1A1MAOA | |
| SCHEMBL30944386 | 0.99 | DYRK1A (0.69) | DYRK1ANPC1RAB9AALDH1A1MAOA | |
| SCHEMBL28530314 | 0.99 | DYRK1A (0.69) | DYRK1ANPC1RAB9AALDH1A1MAOA | |
| SCHEMBL29698982 | 0.89 | DYRK1A (0.60) | DYRK1ANPC1RAB9AALDH1A1MAOA | |
| SCHEMBL28530682 | 0.88 | DYRK1A (0.61) | DYRK1ANPC1RAB9AALDH1A1MAOA | |
| SCHEMBL30944339 | 0.88 | DYRK1A (0.61) | DYRK1ANPC1RAB9AALDH1A1MAOA | |
| SCHEMBL30944367 | 0.88 | MAOA (0.67) | DYRK1ANPC1RAB9AALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |