Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530617 | 0.74 | IKBKB (0.45) | IKBKBKMT2AALDH1A1MEN1HSD17B10 | |
| SCHEMBL27983418 | 0.74 | CCNC (0.51) | IKBKBALDH1A1HSD17B10HPGD | |
| SCHEMBL28542740 | 0.73 | MKNK1 (0.52) | KMT2ACFTR | |
| SCHEMBL18920571 | 0.72 | IKBKB (0.43) | IKBKBKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL28525528 | 0.72 | BTK (0.44) | IKBKBKMT2AALDH1A1MEN1HSD17B10 | |
| SCHEMBL28910335 | 0.71 | AR (0.44) | — | |
| SCHEMBL28531112 | 0.71 | MKNK1 (0.41) | KDM4E | |
| SCHEMBL28529474 | 0.69 | FEN1 (0.34) | — | |
| SCHEMBL28539500 | 0.68 | GRIK1 (0.36) | HPGD | |
| SCHEMBL28531660 | 0.68 | SIRT3 (0.36) | KMT2AALDH1A1MEN1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107311921-B | Aryl or heteroaryl substituted benzene compounds | EPIZYME股份有限公司 | 2021-02-12 | — | — | CN | disclosed |