Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525528 | 0.77 | BTK (0.44) | IKBKBMAPTALDH1A1HSD17B10BTK | |
| SCHEMBL27983418 | 0.76 | CCNC (0.51) | IKBKBALDH1A1HPGDHSD17B10BTK | |
| SCHEMBL27983939 | 0.76 | CHEK2 (0.39) | MAPTALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL28530697 | 0.74 | IKBKB (0.45) | IKBKBMAPTALDH1A1GAAKDM4E | |
| SCHEMBL28542740 | 0.73 | MKNK1 (0.52) | BTKKMT2ALMNACHEK2 | |
| SCHEMBL2417969 | 0.72 | ALDH1A1 (0.49) | IKBKBMAPTALDH1A1GAAKDM4E | |
| SCHEMBL28531112 | 0.71 | MKNK1 (0.41) | KDM4EKEAP1 | |
| SCHEMBL28536246 | 0.70 | PARP1 (0.49) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4452050 | 0.70 | BTK (0.50) | IKBKBMAPTALDH1A1GAAKDM4E | |
| SCHEMBL28529474 | 0.69 | FEN1 (0.34) | PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107311921-B | Aryl or heteroaryl substituted benzene compounds | EPIZYME股份有限公司 | 2021-02-12 | — | — | CN | disclosed |