Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | SLC10A2 | Q12908 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565875 | 0.80 | CYP19A1 (0.40) | SLC10A2MEN1KMT2A | |
| SCHEMBL6221558 | 0.80 | SLC10A2 (0.40) | PTGDR2SLC10A2MEN1CYP3A4KMT2A | |
| SCHEMBL6221561 | 0.80 | SLC10A2 (0.40) | PTGDR2SLC10A2MEN1CYP3A4KMT2A | |
| SCHEMBL6221549 | 0.80 | SLC10A2 (0.40) | PTGDR2SLC10A2MEN1CYP3A4KMT2A | |
| SCHEMBL19117718 | 0.72 | SLC6A2 (0.40) | PTGDR2SLC10A2SLC6A2SLC6A4 | |
| SCHEMBL21266523 | 0.72 | SLC6A2 (0.40) | PTGDR2SLC10A2SLC6A2SLC6A4 | |
| SCHEMBL10858571 | 0.72 | SLC6A2 (0.38) | PTGDR2SLC10A2SLC6A2SLC6A4 | |
| SCHEMBL21032138 | 0.72 | SLC6A2 (0.38) | PTGDR2SLC10A2SLC6A2SLC6A4MEN1 | |
| SCHEMBL12180971 | 0.72 | SLC6A2 (0.40) | PTGDR2SLC10A2SLC6A2SLC6A4 | |
| SCHEMBL10192537 | 0.72 | SLC6A2 (0.38) | PTGDR2SLC10A2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112430228-B | Chiral 2, 3-dihydrobenzo [ b ] thiophene 1, 1-dioxide, derivative and preparation method | 四川大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-112430228-A | Chiral 2, 3-dihydrobenzo [ b ] thiophene 1, 1-dioxide, derivative and preparation method | 四川大学 | 2021-03-02 | — | — | CN | disclosed |