Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD16A | O95870 | 2/20 | 0.49 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855611 | 0.93 | ABHD16A (0.50) | ABHD16AHSPB1NPBWR1MCHR1MGLL | |
| SCHEMBL2853363 | 0.89 | ABHD16A (0.44) | ABHD16AHSPB1ATMTDP1NPBWR1 | |
| SCHEMBL4398899 | 0.84 | ABHD16A (0.65) | ABHD16AALDH1A1LMNASIRT6TDP1 | |
| Hydrochloric Acid SCHEMBL2834123 | 0.83 | ABHD16A (0.52) | ABHD16ANPBWR1MCHR1MGLL | |
| SCHEMBL2854275 | 0.83 | ABHD16A (0.54) | ABHD16ANPBWR1MCHR1MGLL | |
| SCHEMBL2847268 | 0.81 | ABHD16A (0.61) | ABHD16AALDH1A1NPBWR1MCHR1MGLL | |
| SCHEMBL7040780 | 0.81 | ABHD16A (0.63) | ABHD16AATMTDP1MGLL | |
| SCHEMBL2858427 | 0.81 | ABHD16A (0.64) | ABHD16AHSPB1MGLL | |
| SCHEMBL2850915 | 0.79 | ABHD16A (0.50) | ABHD16ANPBWR1MCHR1MGLL | |
| SCHEMBL7043172 | 0.78 | ABHD16A (0.57) | ABHD16AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238131-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - Portela & Ca., S.A. (PT) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009084970-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL-PORTELA & COMPANHIA, S.A. (PT) | 2009-07-09 | — | — | WO | disclosed |