SCHEMBL2854275

SCHEMBL2854275

COc1ccc(-n2nc(Oc3ccc(F)cc3F)oc2=O)cc1N

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ABHD16A O95870 2/20 0.54
MGLL Q99685 2/20 0.43
NPBWR1 P48145 2/20 0.43
MCHR1 Q99705 2/20 0.43
FAAH O00519 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2834123 0.92 ABHD16A (0.52) ABHD16AMGLLNPBWR1MCHR1FAAH
SCHEMBL2847268 0.85 ABHD16A (0.61) ABHD16AMGLLNPBWR1MCHR1FAAH
SCHEMBL2850915 0.83 ABHD16A (0.50) ABHD16AMGLLNPBWR1MCHR1FAAH
SCHEMBL2855611 0.83 ABHD16A (0.50) ABHD16AMGLLNPBWR1MCHR1FAAH
SCHEMBL2853190 0.83 ABHD16A (0.49) ABHD16AMGLLNPBWR1MCHR1
SCHEMBL2851911 0.81 ABHD16A (0.53) ABHD16ANPBWR1MCHR1
SCHEMBL2855537 0.79 ABHD16A (0.51) ABHD16AMGLLNPBWR1MCHR1FAAH
SCHEMBL2858427 0.74 ABHD16A (0.64) ABHD16AMGLL
SCHEMBL2853363 0.74 ABHD16A (0.44) ABHD16AMGLLNPBWR1MCHR1
SCHEMBL7046287 0.72 MGLL (0.57) ABHD16AMGLLNPBWR1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2238131-A1 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE BIAL - Portela & Ca., S.A. (PT) 2010-10-13 EP disclosed
WO-2009084970-A1 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE BIAL-PORTELA & COMPANHIA, S.A. (PT) 2009-07-09 WO disclosed