SCHEMBL2853215

SCHEMBL2853215

CNc1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 2/20 0.79
KCNK9 Q9NPC2 1/20 0.78
MAPT P10636 1/20 0.76
MEN1 O00255 3/20 0.75
KMT2A Q03164 3/20 0.75
HTT P42858 1/20 0.75
RAB9A P51151 1/20 0.75
LMNA P02545 1/20 0.74
PTGS1 P23219 2/20 0.71
P2RX1 P51575 1/20 0.69
RXFP1 Q9HBX9 2/20 0.64
POLB P06746 2/20 0.63
CTDSP1 Q9GZU7 1/20 0.63
TSHR P16473 1/20 0.60
KCNQ3 O43525 1/20 0.60
KCNQ2 O43526 1/20 0.60
KCNE1 P15382 1/20 0.60
KCNQ1 P51787 1/20 0.60
KCNQ5 Q9NR82 1/20 0.60
GAA P10253 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22065210 0.94 MAPT (0.81) KCNK3KCNK9MAPTMEN1KMT2A
SCHEMBL4286068 0.90 MAPT (0.94) KCNK3KCNK9MAPTMEN1KMT2A
SCHEMBL4656855 0.87 MAPT (0.78) KCNK3KCNK9MAPTMEN1KMT2A
SCHEMBL12764063 0.86 MEN1 (1.00) KCNK3KCNK9MAPTMEN1KMT2A
SCHEMBL22065212 0.86 PTGS1 (0.80) KCNK3KCNK9MAPTMEN1KMT2A
SCHEMBL20073524 0.86 MAPT (0.81) KCNK3KCNK9MAPTMEN1KMT2A
SCHEMBL15603515 0.86 MAPT (0.81) KCNK3KCNK9MAPTMEN1KMT2A
SCHEMBL4517587 0.85 LMNA (1.00) KCNK3KCNK9MAPTMEN1KMT2A
SCHEMBL30739929 0.85 LMNA (1.00) KCNK3KCNK9MAPTMEN1KMT2A
SCHEMBL22024848 0.85 KCNK3 (0.73) KCNK3KCNK9MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1846532-B1 ENERGIZED FLUIDS AND METHODS OF USE THEREOF SCHLUMBERGER SERVICES PETROL (FR) 2013-09-18 EP claimed
US-8207094-B2 fluid compositions used in treating a subterranean formation. In particular, the invention is aqueous wellbore treatment compositions which are foams containing a viscosifying agent, a foam extender, a gas component, and a surfactant, as well as methods of forming such fluids, and uses thereof. SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2012-06-26 US claimed
CN-101379160-B Stabilized and freeze-protected polymer drag reducing agent suspensions BAKER HUGHES INC 2012-04-25 CN claimed
US-7781380-B2 Methods of treating subterranean formations with heteropolysaccharides based fluids SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2010-08-24 US claimed
US-7776796-B2 Methods of treating wellbores with recyclable fluids SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2010-08-17 US claimed
EP-1999225-B1 METHODS OF TREATING WELLBORES WITH RECYCLABLE FLUIDS SCHLUMBERGER SERVICES PETROL (FR) 2010-05-12 EP claimed
CN-101379160-A Stabilized and freeze-protected polymer drag reducing agent suspensions BAKER HUGHES INC (US) 2009-03-04 CN claimed
US-7494957-B2 Energized fluids and methods of use thereof SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2009-02-24 US claimed
EP-1994111-A2 STABILIZED AND FREEZE-PROTECTED POLYMER DRAG REDUCING AGENT SUSPENSIONS Baker Hughes Incorporated (US) 2008-11-26 EP claimed
US-20080269080-A1 Wellbore Treatment Compositions Containing Foam Extenders and Methods of Use Thereof HUTCHINS RICHARD D 2008-10-30 US claimed
US-20080026957-A1 Treatment and Production of Subterranean Formations with Heteropolysaccharides SCHLUMBERGER TECHNOLOGY CORPORATION 2008-01-31 US claimed
US-20080004187-A1 Energized Fluids and Methods of Use Thereof PENA ALEJANDRO 2008-01-03 US claimed
US-20070215355-A1 Methods of Treating Wellbores with Recyclable Fluids SCHLUMBERGER TECHNOLOGY CORPORATION 2007-09-20 US claimed
US-20070205392-A1 Stabilized and Freeze-Protected Polymer Drag Reducing Agent Suspensions BAKER HUGHES INCORPORATED (US) 2007-09-06 US claimed
WO-2007092510-A2 STABILIZED AND FREEZE-PROTECTED POLYMER DRAG REDUCING AGENT SUSPENSIONS BAKER HUGHES INCORPORATED (US) 2007-08-16 WO claimed
US-20070042913-A1 Wellbore treatment compositions containing foam extenders and methods of use thereof SCHLUMBERGER TECHNOLOGY CORPORATION 2007-02-22 US claimed
US-20060166837-A1 Methods of treating subterranean formations with heteropolysaccharides based fluids SCHLUMBERGER TECHNOLOGY CORPORATION 2006-07-27 US claimed
US-20060166836-A1 Energized fluids and methods of use thereof SCHLUMBERGER TECHNOLOGY CORPORATION 2006-07-27 US claimed
US-11352354-B2 Substituted penta-fused hexa-heterocyclic compounds, preparation method therefor, drug combination and use thereof XIAMEN UNIVERSITY (CN) 2022-06-07 US disclosed
US-20070042913-A1 Wellbore treatment compositions containing foam extenders and methods of use thereof SCHLUMBERGER TECHNOLOGY CORPORATION 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352354-B2 Substituted penta-fused hexa-heterocyclic compounds, preparation method therefor, drug combination and use thereof PIKFYVE, PIK3CA, PIK3C2A KCNK3 1001/4885KCNK9 1590/4885MAPT 2459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.