Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC2R | Q01718 | 15/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MTTP | P55157 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.35 |
| ▸ | MICA | Q29983 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30138136 | 1.00 | MC2R (0.86) | MC2RKMT2AMRGPRX4MTTPHSD17B3 | |
| SCHEMBL28532806 | 1.00 | MC2R (0.86) | MC2RKMT2AMRGPRX4MTTPHSD17B3 | |
| SCHEMBL21700840 | 0.93 | MC2R (0.88) | MC2RKMT2AMTTP | |
| SCHEMBL21700838 | 0.93 | MC2R (0.88) | MC2RKMT2AMTTP | |
| SCHEMBL21701027 | 0.93 | MC2R (0.87) | MC2RKMT2AMTTPKLRK1MICA | |
| SCHEMBL21701029 | 0.93 | MC2R (0.87) | MC2RKMT2AMTTPKLRK1MICA | |
| SCHEMBL31188918 | 0.93 | MC2R (0.87) | MC2RKMT2AMTTPKLRK1MICA | |
| SCHEMBL21700656 | 0.93 | MC2R (0.89) | MC2RMRGPRX4 | |
| SCHEMBL21700964 | 0.92 | MC2R (1.00) | MC2RKMT2AMRGPRX4 | |
| SCHEMBL21700680 | 0.92 | MC2R (1.00) | MC2RKMT2AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533904-A | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-112533904-B | Melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-112533904-A | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2021-03-19 | — | — | CN | disclosed |