Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 11/20 | 0.43 |
| ▸ | RAB9A | P51151 | 11/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031773 | 0.71 | KDM4E (0.53) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16373701 | 0.70 | NPC1 (0.56) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL22162812 | 0.69 | CA12 (0.58) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL493511 | 0.68 | KDM4E (0.49) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17055934 | 0.68 | NOTUM (0.58) | LMNANPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL21373510 | 0.68 | ALDH1A1 (0.52) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17788472 | 0.68 | NPC1 (0.60) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5563525 | 0.67 | SMN1; SMN2 (0.47) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9431911 | 0.67 | KDM4E (0.68) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6835667 | 0.67 | NPC1 (0.66) | LMNANPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566636-A | Compound and use thereof | 优曼尼蒂治疗公司 | 2021-03-26 | — | — | CN | disclosed |