Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC2R | Q01718 | 15/20 | 0.72 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532126 | 0.95 | MC2R (0.74) | MC2RMRGPRX4MDM2DRD3 | |
| SCHEMBL28539479 | 0.93 | MC2R (0.68) | MC2RMRGPRX4MDM2KMT2A | |
| SCHEMBL28539415 | 0.93 | MC2R (0.68) | MC2RMRGPRX4MDM2KMT2AMAPK8 | |
| SCHEMBL28525340 | 0.92 | MC2R (0.75) | MC2RMRGPRX4MDM2KMT2AMAPK8 | |
| SCHEMBL28536865 | 0.92 | MC2R (0.74) | MC2RMRGPRX4MDM2KMT2AMAPK8 | |
| SCHEMBL28531216 | 0.91 | MC2R (0.69) | MC2RMDM2DRD3 | |
| SCHEMBL28534256 | 0.91 | MC2R (0.73) | MC2RMRGPRX4MDM2KMT2AMAPK8 | |
| SCHEMBL28532866 | 0.91 | MC2R (0.75) | MC2RMRGPRX4MDM2KMT2AMAPK8 | |
| SCHEMBL28532117 | 0.90 | MC2R (0.72) | MC2RMRGPRX4MDM2KMT2AMAPK8 | |
| SCHEMBL28525318 | 0.89 | MC2R (0.70) | MC2RMDM2KMT2AMAPK8MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533904-A | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-112533904-A | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2021-03-19 | — | — | CN | disclosed |