Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | FOS | P01100 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.33 |
| ▸ | S100A10 | P60903 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532694 | 0.93 | MAOB (0.36) | MAOBATMMAPTSMN1; SMN2HPGD | |
| SCHEMBL28537019 | 0.93 | MAOB (0.36) | MAOBATMMAPTSMN1; SMN2HPGD | |
| SCHEMBL28532378 | 0.89 | MAOB (0.38) | MAOBATMMAPTSMN1; SMN2HPGD | |
| SCHEMBL23632853 | 0.87 | ACACB (0.42) | MAOBMAPTSMN1; SMN2HPGDNPC1 | |
| SCHEMBL28525724 | 0.86 | MAOB (0.41) | MAOBATMMAPTSMN1; SMN2HPGD | |
| SCHEMBL28539768 | 0.85 | MAOB (0.38) | MAOBATMMAPTSMN1; SMN2HPGD | |
| SCHEMBL28910595 | 0.85 | MAOB (0.38) | MAOBATMMAPTSMN1; SMN2HPGD | |
| SCHEMBL28535529 | 0.83 | MAOB (0.38) | MAOBATMMAPTSMN1; SMN2HPGD | |
| SCHEMBL28526859 | 0.81 | MAOB (0.38) | MAOBATMMAPTSMN1; SMN2HPGD | |
| SCHEMBL28537468 | 0.81 | MAOB (0.38) | MAOBATMMAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |