Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | AXL | P30530 | 2/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 8/20 | 0.45 |
| ▸ | SYK | P43405 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354306 | 0.97 | KMT2A (0.51) | KMT2AAXLNR2F2NPSR1KDM4E | |
| SCHEMBL26930786 | 0.90 | MERTK (0.47) | KMT2AAXLMAPK8MERTKMAPK9 | |
| SCHEMBL17167992 | 0.90 | MERTK (0.47) | KMT2AAXLMAPK8MERTKMAPK9 | |
| SCHEMBL16435468 | 0.90 | MERTK (0.47) | KMT2AAXLMAPK8MERTKMAPK9 | |
| SCHEMBL14657977 | 0.88 | MAPK8 (0.55) | KMT2AMAPK8SYKOPRK1MAPK9 | |
| SCHEMBL30873290 | 0.88 | MAPK8 (0.55) | KMT2AMAPK8SYKOPRK1MAPK9 | |
| SCHEMBL4070421 | 0.87 | NR2F2 (0.62) | KMT2AAXLNR2F2NPSR1KDM4E | |
| SCHEMBL29501978 | 0.86 | NR2F2 (0.63) | KMT2AAXLNR2F2NPSR1KDM4E | |
| SCHEMBL20299361 | 0.86 | NR2F2 (0.63) | KMT2AAXLNR2F2NPSR1KDM4E | |
| SCHEMBL31360739 | 0.86 | KMT2A (0.57) | KMT2AAXLNR2F2NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586356-B | Ribociclib new intermediate and synthetic method for preparing Ribociclib by using same | 杭州科巢生物科技有限公司 | 2021-02-19 | — | — | CN | disclosed |