Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | GAA | P10253 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537107 | 0.81 | MAPT (0.49) | MAPTKMT2AMEN1GAARAB9A | |
| SCHEMBL28908620 | 0.80 | MAPT (0.62) | MAPTKMT2AMEN1GAARAB9A | |
| SCHEMBL28541968 | 0.78 | MAPT (0.45) | MAPTKMT2AMEN1GAARAB9A | |
| SCHEMBL10112300 | 0.73 | MAPT (1.00) | MAPTKMT2AMEN1GAARAB9A | |
| SCHEMBL31429960 | 0.73 | MAPT (1.00) | MAPTKMT2AMEN1GAARAB9A | |
| SCHEMBL28530639 | 0.72 | KMT2A (0.62) | MAPTKMT2AMEN1GAARAB9A | |
| SCHEMBL12767379 | 0.72 | MAPT (0.53) | MAPTKMT2AMEN1GAARAB9A | |
| SCHEMBL20278420 | 0.71 | GFER (0.53) | MAPTKMT2AMEN1GAARAB9A | |
| SCHEMBL20283691 | 0.71 | KMT2A (0.67) | MAPTKMT2AMEN1GAARAB9A | |
| SCHEMBL21519608 | 0.71 | KMT2A (0.48) | MAPTKMT2AMEN1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480004-A | 5-trifluoromethyl substituted pyrazole derivative and synthesis method and application thereof | 华南理工大学 | 2021-03-12 | — | — | CN | disclosed |