Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.59 |
| ▸ | LMNA | P02545 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530639 | 0.87 | KMT2A (0.62) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL11048473 | 0.81 | MAPT (0.58) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL11048471 | 0.81 | MAPT (0.58) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL3196378 | 0.81 | MEN1 (0.72) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL28537107 | 0.80 | MAPT (0.49) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL28533381 | 0.80 | MAPT (0.57) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL24265387 | 0.78 | MAPT (0.50) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL3065879 | 0.77 | MAPT (0.62) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL734791 | 0.77 | KMT2A (1.00) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL3065881 | 0.77 | MAPT (0.62) | MAPTKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480004-B | 5-trifluoromethyl substituted pyrazole derivative and synthesis method and application thereof | 华南理工大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-112480004-A | 5-trifluoromethyl substituted pyrazole derivative and synthesis method and application thereof | 华南理工大学 | 2021-03-12 | — | — | CN | disclosed |