Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574591 | 0.81 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL13735039 | 0.80 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL395631 | 0.80 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL27855900 | 0.77 | HTT (0.41) | KMT2A | |
| SCHEMBL27440249 | 0.77 | ESR2 (0.46) | — | |
| SCHEMBL27501867 | 0.77 | GRIA4 (0.43) | KMT2A | |
| SCHEMBL10751693 | 0.76 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL10736010 | 0.76 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL10751690 | 0.76 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL418730 | 0.76 | MEN1 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538084-A | Novel KRAS G12C protein inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2021-03-23 | — | — | CN | disclosed |