Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614876 | 0.92 | GABRA1 (0.39) | GABRA1GABRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18668719 | 0.92 | KMT2A (0.40) | GABRA1GABRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11422337 | 0.91 | GABRA1 (0.40) | GABRA1GABRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL251314 | 0.91 | PTGDR2 (0.40) | GABRA1GABRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28508389 | 0.82 | GABRA1 (0.58) | GABRA1GABRB2KDM4EALDH1A1LMNA | |
| SCHEMBL17594282 | 0.80 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL9915277 | 0.78 | TLR8 (0.41) | SLC6A2SLC6A4SLC6A3ALDH1A1HPGD | |
| SCHEMBL3265467 | 0.78 | GAA (0.39) | GABRA1GABRB2KDM4EALDH1A1LMNA | |
| SCHEMBL83597 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2KDM4EALDH1A1LMNA | |
| SCHEMBL2913534 | 0.77 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484347-B | Preparation method of cyclopropanation of terminal isoprene compound | 江苏八巨药业有限公司 | 2021-02-05 | — | — | CN | disclosed |