Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712775 | 0.90 | MYC (0.54) | GRM2KMT2APTGER1MYCSMN1; SMN2 | |
| SCHEMBL1712768 | 0.82 | TSHR (0.56) | KMT2AMAPTSLC6A4SLC6A3HSP90AA1 | |
| SCHEMBL11080302 | 0.79 | EIF4E (0.52) | GRM2KMT2APTGER1MYCSMN1; SMN2 | |
| SCHEMBL30984364 | 0.79 | NPC1 (0.49) | GRM2KMT2ASMN1; SMN2S100A4MEN1 | |
| SCHEMBL13176936 | 0.79 | NPC1 (0.49) | GRM2KMT2ASMN1; SMN2S100A4MEN1 | |
| SCHEMBL11082147 | 0.79 | CYP2C8 (0.54) | MAPTSMN1; SMN2HSP90AA1GABRPGABRD | |
| SCHEMBL4437961 | 0.79 | MAPK13 (0.55) | RECQLKMT2AKCNMA1MAPTMEN1 | |
| SCHEMBL4434910 | 0.79 | RECQL (0.53) | RECQLKCNMA1MAPTALDH1A1 | |
| SCHEMBL17454062 | 0.78 | PTGER1 (0.55) | KMT2APTGER1MYCSMN1; SMN2CHRM1 | |
| SCHEMBL27529145 | 0.77 | ALDH1A1 (0.50) | KMT2AMYCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586447-B | Benzodiazepine compound and preparation method and application thereof | 中国人民解放军第四军医大学 | 2021-01-29 | — | — | CN | disclosed |