Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 16/20 | 0.53 |
| ▸ | NHERF1 | O14745 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634221 | 1.00 | PYGL (0.53) | PYGLNHERF1MEN1KMT2ARXFP1 | |
| SCHEMBL28525293 | 0.94 | PYGL (0.52) | PYGLNHERF1MEN1KMT2ARXFP1 | |
| SCHEMBL29634300 | 0.94 | PYGL (0.52) | PYGLNHERF1MEN1KMT2ARXFP1 | |
| SCHEMBL29634122 | 0.92 | PYGL (0.50) | PYGLNHERF1MEN1KMT2ARXFP1 | |
| SCHEMBL28536248 | 0.92 | PYGL (0.50) | PYGLNHERF1MEN1KMT2ARXFP1 | |
| SCHEMBL29634368 | 0.91 | PYGL (0.49) | PYGLNHERF1MEN1KMT2ARXFP1 | |
| SCHEMBL28531599 | 0.91 | PYGL (0.49) | PYGLNHERF1MEN1KMT2ARXFP1 | |
| SCHEMBL28524834 | 0.88 | MEN1 (0.54) | PYGLNHERF1MEN1KMT2ARXFP1 | |
| SCHEMBL29634197 | 0.88 | MEN1 (0.54) | PYGLNHERF1MEN1KMT2ARXFP1 | |
| SCHEMBL28518517 | 0.80 | PYGL (0.53) | PYGLNHERF1MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112442022-B | Benzoxazine-4-ketone compound, preparation method and medical application thereof | 承德医学院 | 2022-05-20 | — | — | CN | disclosed |
| CN-112442022-A | Benzoxazine-4-ketone compound, preparation method and medical application thereof | 承德医学院 | 2021-03-05 | — | — | CN | disclosed |