Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.68 |
| ▸ | PIK3CD | O00329 | 18/20 | 0.68 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.64 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.64 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.62 |
| ▸ | GAK | O14976 | 1/20 | 0.62 |
| ▸ | PRKACG | P22612 | 1/20 | 0.62 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11938364 | 0.96 | PIK3CA (0.74) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938363 | 0.90 | PIK3CA (0.77) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938365 | 0.88 | PIK3CA (0.75) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938426 | 0.83 | PIK3CA (0.77) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL13030361 | 0.81 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL13768119 | 0.81 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL28538508 | 0.81 | PIK3CA (0.71) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL22600055 | 0.79 | PIK3CA (0.89) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938370 | 0.79 | PIK3CA (0.77) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB | |
| SCHEMBL11938434 | 0.79 | PIK3CA (0.84) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112472699-A | Combination methods for improving the therapeutic benefit of bisantrene and derivatives | 种族肿瘤学公司 | 2021-03-12 | — | — | CN | disclosed |