Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526594 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CTPS1MAPTRAB9A | |
| SCHEMBL30947754 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CTPS1MAPTRAB9A | |
| SCHEMBL30947741 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CTPS1MAPTRAB9A | |
| SCHEMBL28526592 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CTPS1MAPTRAB9A | |
| SCHEMBL28526591 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CTPS1MAPTRAB9A | |
| SCHEMBL28534785 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CTPS1MAPTRAB9A | |
| SCHEMBL28528127 | 0.90 | MAPT (0.44) | ALDH1A1CTPS1MAPTRAB9AMEN1 | |
| SCHEMBL28528125 | 0.90 | MAPT (0.44) | ALDH1A1CTPS1MAPTRAB9AMEN1 | |
| SCHEMBL28534043 | 0.90 | MAPT (0.44) | ALDH1A1CTPS1MAPTRAB9AMEN1 | |
| SCHEMBL28534040 | 0.90 | MAPT (0.44) | ALDH1A1CTPS1MAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |
| CN-112469707-A | Prophylactic or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2021-03-09 | — | — | CN | disclosed |