Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30431090 | 1.00 | LMNA (0.44) | LMNAMAPTALDH1A1PDK2ABCB1 | |
| SCHEMBL29628994 | 0.82 | ABCB1 (0.48) | LMNAMAPTALDH1A1PDK2ABCB1 | |
| SCHEMBL20231723 | 0.82 | ABCB1 (0.48) | LMNAMAPTALDH1A1PDK2ABCB1 | |
| SCHEMBL2386587 | 0.78 | SUV39H2 (0.55) | LMNAMAPTALDH1A1PDK2ABCB1 | |
| SCHEMBL30726275 | 0.78 | SUV39H2 (0.55) | LMNAMAPTALDH1A1PDK2ABCB1 | |
| SCHEMBL31216276 | 0.77 | ABCB1 (0.50) | LMNAMAPTALDH1A1ABCB1SUV39H2 | |
| SCHEMBL31216180 | 0.76 | ABCB1 (0.50) | LMNAMAPTALDH1A1ABCB1SUV39H2 | |
| SCHEMBL12663222 | 0.74 | ABCB1 (0.58) | LMNAMAPTALDH1A1PDK2ABCB1 | |
| SCHEMBL23784871 | 0.74 | MAPT (0.57) | LMNAMAPTALDH1A1PDK2GPR119 | |
| SCHEMBL20046122 | 0.74 | ABCB1 (0.50) | LMNAMAPTALDH1A1PDK2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112262134-B | Cerebulin ligands and bifunctional compounds comprising same | 阿尔维纳斯运营股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-111892577-B | Compounds and methods for androgen receptor targeted degradation | 阿尔维纳斯运营股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-112262134-A | Cereblon ligand and bifunctional compound comprising same | 阿尔维纳斯运营股份有限公司 | 2021-01-22 | — | — | CN | disclosed |
| CN-111892577-A | Compounds and methods for targeted degradation of androgen receptor | 阿尔维纳斯运营股份有限公司 | 2020-11-06 | — | — | CN | disclosed |