Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526071 | 0.87 | MEN1 (0.57) | TP53EGFRMAPTPDK1PDK2 | |
| SCHEMBL30589867 | 0.82 | GAA (0.55) | TP53MAPTALDH1A1MAPK1HTT | |
| SCHEMBL11842708 | 0.79 | MMP1 (0.66) | EGFRALDH1A1HPGDPDK1PDK2 | |
| SCHEMBL11336614 | 0.79 | EGFR (0.59) | TP53EGFRMAPTALDH1A1HPGD | |
| SCHEMBL31162463 | 0.79 | EGFR (0.59) | TP53EGFRMAPTALDH1A1HPGD | |
| SCHEMBL11842713 | 0.79 | MMP1 (0.66) | EGFRALDH1A1HPGDPDK1PDK2 | |
| SCHEMBL2095754 | 0.79 | MAPT (0.59) | TP53EGFRMAPTALDH1A1HPGD | |
| SCHEMBL22367616 | 0.77 | TP53 (0.76) | TP53EGFRMAPTALDH1A1HPGD | |
| SCHEMBL22367617 | 0.77 | TP53 (0.76) | TP53EGFRMAPTALDH1A1HPGD | |
| SCHEMBL22623158 | 0.77 | TP53 (0.76) | TP53EGFRMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112472699-A | Combination methods for improving the therapeutic benefit of bisantrene and derivatives | 种族肿瘤学公司 | 2021-03-12 | — | — | CN | disclosed |