Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538426 | 0.85 | BACE1 (0.47) | BACE1ESR1ESR2DYRK3CLK1 | |
| SCHEMBL2080 | 0.73 | ALDH1A1 (0.35) | BACE1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL3141049 | 0.72 | ALDH1A1 (0.41) | MAPTALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL28399583 | 0.71 | ALDH1A1 (0.33) | BACE1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL29103760 | 0.71 | ALDH1A1 (0.33) | BACE1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL2356812 | 0.71 | CYP1A2 (0.42) | BACE1GAAKDM4EMEN1KMT2A | |
| SCHEMBL206447 | 0.71 | BACE1 (0.38) | BACE1DYRK1ANPC1CYP11B1CYP11B2 | |
| SCHEMBL2255694 | 0.69 | ESR2 (0.42) | BACE1ESR1ESR2DYRK3CLK1 | |
| SCHEMBL2253487 | 0.69 | ESR2 (0.42) | BACE1ESR1ESR2DYRK3CLK1 | |
| SCHEMBL29093556 | 0.68 | ESR1 (0.46) | BACE1ESR1ESR2DYRK3CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716555-A | Compounds and compositions for targeting EGFR expressing tumors | 博笛生物科技有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114671954-A | Compounds and compositions targeting HER2 positive tumors | 博笛生物科技有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-113633783-A | Compounds and compositions for immunotherapy | 博笛生物科技有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-105899539-B | Compounds and compositions for immunotherapy | 博笛生物科技有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-112587672-A | anti-PD-L1 conjugates for the treatment of tumors | 博笛生物科技有限公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-112546230-A | Combination therapeutic compositions and combination therapeutic methods for treating cancer | 博笛生物科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112546231-A | Combination therapeutic compositions and combination therapeutic methods for treating cancer | 博笛生物科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112546238-A | anti-PD-L1 conjugates for the treatment of tumors | 博笛生物科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-109152832-A | Anti-CD 20 for treating tumour combines | 博笛生物科技有限公司 | 2019-01-04 | — | — | CN | disclosed |