Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.65 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.65 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 0.65 |
| ▸ | ADORA1 known ✓ | P30542 | 1/20 | 0.65 |
| ▸ | MARS1 | P56192 | 4/20 | 0.72 |
| ▸ | DOT1L | Q8TEK3 | 6/20 | 0.71 |
| ▸ | NSD2 | O96028 | 5/20 | 0.71 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.71 |
| ▸ | SETD7 | Q8WTS6 | 4/20 | 0.71 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.71 |
| ▸ | NNMT | P40261 | 3/20 | 0.71 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.71 |
| ▸ | FASN | P49327 | 3/20 | 0.71 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.71 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.71 |
| ▸ | INMT | O95050 | 2/20 | 0.71 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.71 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.71 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL28544361 | 1.00 | MARS1 (0.72) | MARS1DOT1LNSD2CARM1SETD7 | |
| Adenosine SCHEMBL3014288 | 0.97 | MARS1 (0.77) | MARS1DOT1LNSD2CARM1SETD7 | |
| Adenosine SCHEMBL27500408 | 0.97 | MARS1 (0.77) | MARS1DOT1LNSD2CARM1SETD7 | |
| Adenosine SCHEMBL3014297 | 0.97 | MARS1 (0.77) | MARS1DOT1LNSD2CARM1SETD7 | |
| Adenosine SCHEMBL27683410 | 0.96 | MARS1 (0.75) | MARS1DOT1LNSD2CARM1SETD7 | |
| Adenosine SCHEMBL25303131 | 0.94 | MARS1 (0.67) | MARS1DOT1LNSD2CARM1SETD7 | |
| Adenosine SCHEMBL28733069 | 0.93 | MARS1 (0.72) | MARS1DOT1LNSD2CARM1SETD7 | |
| Adenosine SCHEMBL28664700 | 0.92 | MARS1 (0.64) | MARS1DOT1LNSD2CARM1SETD7 | |
| Adenosine SCHEMBL29735027 | 0.90 | MARS1 (0.74) | MARS1DOT1LNSD2CARM1SETD7 | |
| Racemethionine SCHEMBL28493813 | 0.89 | MARS1 (0.75) | MARS1DOT1LNSD2CARM1SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341508-B | Separation and purification method of ademetionine | 内蒙古拜克生物有限公司 | 2021-12-03 | — | — | CN | claimed |
| CN-112341508-A | Separation and purification method of ademetionine | 内蒙古拜克生物有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-112341508-B | Separation and purification method of ademetionine | 内蒙古拜克生物有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-112341508-A | Separation and purification method of ademetionine | 内蒙古拜克生物有限公司 | 2021-02-09 | — | — | CN | disclosed |