Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416763 | 0.83 | CYP1A1 (0.55) | MEN1HTTKMT2ANPSR1GAA | |
| SCHEMBL27985505 | 0.83 | GAA (0.59) | MEN1HTTKMT2ANPSR1POLB | |
| SCHEMBL27985059 | 0.82 | MAPT (0.57) | MEN1HTTKMT2ANPSR1POLB | |
| SCHEMBL27985502 | 0.81 | ALDH1A1 (0.53) | MEN1HTTKMT2ANPSR1POLB | |
| SCHEMBL28535465 | 0.81 | KMT2A (0.66) | MEN1HTTKMT2ANPSR1POLB | |
| SCHEMBL61366 | 0.81 | MEN1 (0.50) | MEN1HTTKMT2ANPSR1POLB | |
| SCHEMBL1160797 | 0.81 | MAPT (0.53) | MEN1HTTKMT2ANPSR1POLB | |
| SCHEMBL3953245 | 0.81 | MAPT (0.59) | MEN1HTTKMT2ANPSR1GAA | |
| SCHEMBL5622569 | 0.81 | SMN1; SMN2 (0.69) | MEN1HTTKMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL2093671 | 0.80 | POLB (0.76) | MEN1HTTKMT2ANPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341368-B | Method for synthesizing alpha-fluorinated thioacrylamide derivative | 温州大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-113402412-A | (E) Method for synthesizing (beta) -fluoroacrylamide derivative | 温州大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-112341368-A | Method for synthesizing alpha-fluorinated thioacrylamide derivative | 温州大学 | 2021-02-09 | — | — | CN | disclosed |