Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27272 | 0.77 | KDM4E (0.37) | KDM4EKMT2ALMNA | |
| SCHEMBL7998472 | 0.74 | KDM4E (0.34) | KDM4EKMT2A | |
| SCHEMBL28906292 | 0.74 | LMNA (0.33) | KDM4ELMNA | |
| SCHEMBL1684239 | 0.73 | KDM4E (0.37) | KDM4ELMNA | |
| SCHEMBL4097938 | 0.73 | LMNA (0.39) | KDM4ELMNA | |
| SCHEMBL28266642 | 0.73 | KDM4E (0.32) | KDM4E | |
| SCHEMBL28404636 | 0.72 | KDM4E (0.33) | KDM4E | |
| SCHEMBL28134578 | 0.71 | KDM4E (0.35) | KDM4EKMT2A | |
| SCHEMBL28473411 | 0.70 | KDM4E (0.34) | KDM4E | |
| SCHEMBL29998153 | 0.68 | KDM4E (0.46) | KDM4EKMT2AHTR3EHTR3BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513037-A | Fused ring derivatives useful as FGFR4 inhibitors | 北京加科思新药研发有限公司 | 2021-03-16 | — | — | CN | disclosed |