Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 20/20 | 0.70 |
| ▸ | CDK6 | Q00534 | 19/20 | 0.70 |
| ▸ | CSF1R | P07333 | 11/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.51 |
| ▸ | CDK2 | P24941 | 4/20 | 0.51 |
| ▸ | CCNK | O75909 | 2/20 | 0.51 |
| ▸ | CDK9 | P50750 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28534972 | 0.85 | CDK4 (0.75) | CDK4CDK6CSF1RPIK3CDCCNA2 | |
| SCHEMBL21245866 | 0.84 | CDK4 (0.72) | CDK4CDK6CSF1RPIK3CDCCNA2 | |
| SCHEMBL28619511 | 0.83 | CDK6 (0.69) | CDK4CDK6CSF1RPIK3CD | |
| SCHEMBL30198708 | 0.83 | CDK6 (1.00) | CDK4CDK6CSF1RPIK3CDCCNA2 | |
| SCHEMBL21245653 | 0.83 | CDK6 (1.00) | CDK4CDK6CSF1RPIK3CDCCNA2 | |
| SCHEMBL28536128 | 0.81 | CDK4 (0.72) | CDK4CDK6CSF1RPIK3CDCCNA2 | |
| SCHEMBL26619856 | 0.72 | CTSC (0.39) | CDK4CDK6CSF1RPIK3CDCCNA2 | |
| SCHEMBL21245785 | 0.72 | CDK4 (0.71) | CDK4CDK6CSF1RPIK3CDCCNA2 | |
| SCHEMBL26619999 | 0.70 | BRD4 (0.50) | CDK6CDK2CCNKCDK9 | |
| SCHEMBL21245580 | 0.70 | CDK4 (1.00) | CDK4CDK6CSF1RPIK3CDCCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334451-A | Heterocyclic compounds as kinase inhibitors | 诺维逊生物股份有限公司 | 2021-02-05 | — | — | CN | disclosed |