Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 20/20 | 1.00 |
| ▸ | CDK4 | P11802 | 14/20 | 1.00 |
| ▸ | CSF1R | P07333 | 5/20 | 0.70 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.70 |
| ▸ | CCND3 | P30281 | 8/20 | 0.67 |
| ▸ | CCND1 | P24385 | 5/20 | 0.67 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.67 |
| ▸ | CDK2 | P24941 | 7/20 | 0.67 |
| ▸ | PIM1 | P11309 | 5/20 | 0.64 |
| ▸ | CDK1 | P06493 | 5/20 | 0.60 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.60 |
| ▸ | CDK9 | P50750 | 2/20 | 0.59 |
| ▸ | CCNK | O75909 | 1/20 | 0.59 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.58 |
| ▸ | CDK7 | P50613 | 1/20 | 0.58 |
| ▸ | CCNH | P51946 | 1/20 | 0.58 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21245653 | 1.00 | CDK6 (1.00) | CDK6CDK4CSF1RPIK3CDCCND3 | |
| SCHEMBL21245866 | 0.84 | CDK4 (0.72) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL21245614 | 0.83 | CDK4 (1.00) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL28536123 | 0.83 | CDK4 (0.70) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL21245697 | 0.80 | CDK4 (1.00) | CDK6CDK4CSF1RPIK3CDCCNA2 | |
| SCHEMBL24482652 | 0.80 | CDK6 (0.67) | CDK6CDK4CCND3CCND1CCNA2 | |
| SCHEMBL29684372 | 0.80 | CDK6 (0.67) | CDK6CDK4CCND3CCND1CCNA2 | |
| Hydrochloric Acid SCHEMBL29896942 | 0.80 | CDK6 (0.98) | CDK6CDK4CSF1RPIK3CDCCND3 | |
| Hydrochloric Acid SCHEMBL28600803 | 0.80 | CDK6 (0.98) | CDK6CDK4CSF1RPIK3CDCCND3 | |
| SCHEMBL21245690 | 0.80 | CDK4 (1.00) | CDK6CDK4CSF1RPIK3CDCCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230062022-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC (US) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230062022-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | CDK4, CDK6, CDK8 | CDK6 2/4885CDK4 1/4885CSF1R 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.