Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28250190 | 0.86 | POLB (0.54) | ALDH1A1SMN1; SMN2NPC1RAB9ACA1 | |
| SCHEMBL28525768 | 0.85 | NPC1 (0.57) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28250055 | 0.84 | F10 (0.54) | MAPTF10ALDH1A1GAAKDM4E | |
| SCHEMBL28250048 | 0.82 | RAB9A (0.51) | MAPTKDM4ENPC1RAB9AKMT2A | |
| SCHEMBL28908852 | 0.82 | POLB (0.53) | MAPTALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL1969125 | 0.81 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1969127 | 0.81 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1970964 | 0.81 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4474873 | 0.81 | KMT2A (0.61) | MAPTALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL4474867 | 0.81 | KMT2A (0.61) | MAPTALDH1A1GAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752232-B | Synthetic method of alpha-quaternary carbon amino acid | 四川大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-108752232-A | A kind of synthetic method of α-quaternary carbon amino acid | 四川大学 | 2018-11-06 | — | — | CN | disclosed |